Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme present in every living cell, functioning as a critical electron carrier in oxidative phosphorylation and as a substrate for sirtuins, PARPs, and CD38. Biological systems regulating DNA repair, gene expression, circadian rhythm, and cellular stress response. Hudson Science’s 1000mg lyophilized vial delivers double the concentration of CSD’s existing NAD+ listings: sitting above the 500mg nasal spray and establishing the highest concentration NAD+ presentation in CSD’s range, suited to research protocols requiring maximum compound availability from a single vial supply or examining NAD+ repletion at the highest concentration points in the dose response curve.
The lyophilized vial format at 1000mg serves a distinct research purpose from the 500mg nasal spray presentation. The nasal spray’s intranasal delivery route provides proximity to the olfactory epithelium and potential CNS access via the olfactory nerve pathway. A pharmacokinetically relevant delivery characteristic for research examining NAD+ bioavailability in brain tissue. The 1000mg lyophilized vial’s reconstitute format supports parenteral administration research, in vitro cell culture applications, and high dose repletion protocols where the intact coenzyme is delivered directly into systemic circulation bypassing the metered 5mg per spray delivery constraint of the nasal format. At 1000mg total this vial provides 200 times the per administration compound availability of a single nasal spray dose. Supporting research designs examining NAD+ repletion at the high dose parenteral concentration ranges referenced in clinical intravenous NAD+ literature.
NAD+’s research scope spans mitochondrial function and biogenesis, DNA damage repair through PARP enzyme activity, neurodegeneration and neuroprotection, metabolic syndrome, cellular senescence, and its well documented decline with age across multiple tissue types. The 1000mg concentration of this Hudson Science formulation supports research across the full breadth of NAD+ biological activity including high dose intravenous repletion protocols examining addiction recovery, chronic fatigue, neurodegenerative disease models, and systemic NAD+ deficiency correction where lower concentration formats would require multiple units per administration to achieve equivalent compound delivery.
Hudson Science formulations are stocked by Canada Steroid Depot following the same rigorous third party lab verification process applied to every product in our range. Each batch is tested for concentration accuracy and purity before being made available, with COA documentation available on request. CSD stocks NAD+ across three distinct formats and concentrations: the 500mg nasal spray, and this 1000mg lyophilized vial. This gives researchers delivery route and concentration flexibility from a single verified Canadian supplier. All orders ship discreetly across Canada in plain, unmarked packaging with no identifying information on the exterior.
Reconstitute with bacteriostatic water prior to use. Store lyophilized vial at 2–8°C away from direct light. Once reconstituted refrigerate and use within 28 days. Intended for research purposes only.
Commonly researched alongside MOTS-C, SS-31, and Glutathione in comparative mitochondrial function, longevity, and cellular energy metabolism studies. Browse CSD’s full peptide and research compound range for complete sourcing.
