GHK-Cu (Copper Tripeptide 1) is a naturally occurring copper binding tripeptide consisting of glycine, histidine, and lysine; found in human plasma, saliva, and urine where its plasma concentration declines significantly with age, from approximately 200ng/mL in young adults to under 80ng/mL by age 60. Hudson Science’s formulation supplies 50mg as a lyophilized vial, a high concentration standalone presentation suited to extended research protocols or laboratory applications requiring significant compound availability, and the same concentration included as a component in CSD’s iLab Pharma Anti Aging Peptide Stack.
GHK-Cu’s biological activity is driven by two complementary mechanisms; the tripeptide sequence itself and the copper ion it chelates. The GHK peptide sequence activates a broad range of tissue remodeling and repair pathways including collagen and elastin synthesis stimulation, metalloproteinase modulation for extracellular matrix remodeling, wound healing through keratinocyte and fibroblast activation, and antioxidant activity through superoxide dismutase upregulation. The bound copper ion contributes additional biological activity beyond the peptide sequence. Copper is an essential cofactor for lysyl oxidase, the enzyme responsible for cross linking collagen and elastin fibers into structurally stable extracellular matrix, and for cytochrome c oxidase in the mitochondrial electron transport chain. This dual peptide and copper activity profile makes GHK-Cu mechanistically distinct from copper free tissue repair peptides and from copper compounds lacking the GHK targeting sequence.
GHK-Cu’s research profile spans an unusually broad range of biological systems for a tripeptide compound. Skin biology and wound healing research represents its most extensively documented area. Collagen synthesis stimulation, skin thickness restoration, and wound contraction acceleration have been studied across multiple preclinical and clinical models. Beyond dermal tissue, GHK-Cu has accumulated research literature in nerve tissue repair, lung tissue remodeling, anti inflammatory cytokine modulation, and gene expression regulation, with documented influence on over 4,000 human genes in microarray studies, a breadth of transcriptional activity that has positioned it as one of the most extensively studied naturally occurring tripeptides in contemporary regenerative biology research.
Hudson Science formulations are stocked by Canada Steroid Depot following the same rigorous third party lab verification process applied to every product in our range. Each batch is tested for concentration accuracy and purity before being made available, with COA documentation available on request. CSD stocks GHK-Cu as this standalone 50mg lyophilized vial alongside its inclusion in the Anti Aging Peptide Stack, the Glow Pen, the GLOW Protocol vial, and the KLOW Pen and KLOW Protocol combination formats. Giving researchers the flexibility to source GHK-Cu in isolation or within multi peptide regenerative blends from a single verified Canadian supplier. All orders ship discreetly across Canada in plain, unmarked packaging with no identifying information on the exterior.
Reconstitute with bacteriostatic water prior to use. Store lyophilized peptide at 2–8°C away from direct light. Once reconstituted refrigerate and use within 28 days. Intended for research purposes only.
Commonly researched alongside BPC-157 and TB-500 in tissue repair, regenerative, and skin biology research contexts. Browse CSD’s full peptide range for complete sourcing.
