PCT / HCG / HMG - Post Cycle Therapy
Buy post cycle therapy (PCT) compounds in Canada! Nolvadex (Tamoxifen), Clomid (Clomiphene), Aromasin (Exemestane), HCG and more, shipped domestically from within Canada. Every compound is third party HPLC tested with a certificate of analysis on file. The most complete PCT catalogue available from a domestic Canadian supplier.
Canada's most trusted domestic source for post cycle therapy. Restore endogenous testosterone production, manage estrogen rebound, and protect your HPG axis recovery. All compounds sourced, tested, and dispatched same day from within Canada with no customs and no cross border delays.
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Post Cycle Therapy in Canada | PCT Compounds, Protocols & HPG Axis Recovery
Post cycle therapy (PCT) refers to the use of specific pharmaceutical compounds following a suppressive anabolic steroid cycle to restore endogenous testosterone production, normalize the hypothalamic pituitary gonadal (HPG) axis, and manage estrogen rebound during the recovery period. Canada Steroid Depot stocks the complete range of PCT compounds used across the most researched recovery protocols. SERMs, aromatase inhibitors, and gonadotropins sourced from verified suppliers and independently tested before listing.
Why is post cycle therapy necessary?
Exogenous anabolic steroids suppress the HPG axis through negative feedback on the hypothalamus and pituitary gland. Reducing or eliminating GnRH, LH, and FSH secretion. Without LH stimulation, testicular testosterone production ceases and testicular atrophy can occur over time. When the exogenous androgen is discontinued, the HPG axis does not immediately resume normal function. It can take weeks to months for endogenous testosterone production to recover without intervention. PCT compounds accelerate this recovery by stimulating the HPG axis at the hypothalamic, pituitary, or testicular level, reducing the duration and severity of the low testosterone period between cycle cessation and full recovery.
SERMs; the foundation of PCT
Selective estrogen receptor modulators (SERMs) are the cornerstone of most PCT protocols. By blocking estrogen receptors in the hypothalamus, SERMs remove the negative feedback signal that suppresses GnRH secretion; triggering a cascade of increased GnRH, LH, FSH, and ultimately endogenous testosterone production. Nolvadex (Tamoxifen Citrate) and Clomid (Clomiphene Citrate) are the two most extensively researched SERMs for PCT. Nolvadex is generally preferred as the primary SERM due to its superior side effect profile. Clomid is often added at lower doses for its direct pituitary stimulation effect. Raloxifene is used as an alternative particularly for gynecomastia management during PCT.
HCG in PCT | testicular priming
Human Chorionic Gonadotropin (HCG) is frequently incorporated into PCT protocols as a testicular priming agent; used before or alongside SERMs to restore testicular sensitivity and intratesticular testosterone production. During a suppressive cycle, Leydig cells can become desensitized to LH stimulation. A short course of HCG (typically 500–1000IU every other day for 2–3 weeks) prior to SERM based PCT restores testicular LH receptor sensitivity, making the subsequent SERM phase more effective. HCG should not be run for extended periods during PCT as it maintains pituitary suppression. It is a bridge to SERM therapy, not a replacement for it.
Aromatase inhibitors during PCT
As testosterone production recovers during PCT, aromatization to estrogen can increase. Potentially causing estrogen rebound symptoms and re suppressing the HPG axis through estrogen mediated negative feedback. A mild aromatase inhibitor such as Aromasin (Exemestane) is often included in PCT protocols to manage this rebound estrogen without over suppressing estrogen to the degree that bone mineral density, libido, or lipid profiles are negatively impacted. Aromasin is preferred over Arimidex or Letrozole in PCT due to its steroidal mechanism. As a suicidal AI it does not cause estrogen rebound on discontinuation.
Frequently asked questions
CSD stocks Nolvadex (Tamoxifen Citrate), Clomid (Clomiphene Citrate), Raloxifene, Aromasin (Exemestane), Anastrozole (Arimidex), HCG, and HMG for PCT protocols. Check the category page for current availability and stock status.
PCT start timing depends on the half-life of the compounds used in the cycle. For long ester compounds such as Testosterone Enanthate or Cypionate, PCT typically begins 2 weeks after the last injection. For short ester compounds such as Testosterone Propionate, PCT can begin 3–4 days after the last injection. If HCG is being used as a testicular primer, it is typically run in the 2 week window between last injection and SERM based PCT commencement.
Most research based PCT protocols run for 4–6 weeks. A common protocol is Nolvadex at 40mg per day for weeks 1–2, then 20mg per day for weeks 3–4. Clomid is often run concurrently at 50mg per day for weeks 1–2, then 25mg per day for weeks 3–4. Blood work at the end of PCT and 4 weeks post PCT is recommended to confirm HPG axis recovery.
HCG is not mandatory for PCT but is strongly recommended following longer or more suppressive cycles, or where testicular atrophy has occurred during the cycle. A 2–3 week HCG priming phase before commencing SERM based PCT significantly improves recovery outcomes in research contexts by restoring testicular LH receptor sensitivity before SERMs stimulate LH secretion.
CSD stocks both pharmaceutical grade products from licensed manufacturers and compounds from verified domestic suppliers. All products are independently HPLC tested for concentration accuracy regardless of source. Pharma grade products are clearly identified in each listing.
All PCT orders ship from within Canada via tracked Canada Post or courier. Packages are plain and discreet with no identifying product information on the exterior. Most orders arrive within 2–5 business days depending on your province. Express shipping is available at checkout. Orders over $250 qualify for free shipping Canada wide.