5-Amino-1MQ – 10mg

5-Amino-1MQ (5-Amino 1 methylquinolinium) is a selective small molecule inhibitor of nicotinamide N-methyltransferase (NNMT);  an enzyme that plays a central regulatory role in cellular energy metabolism, adipogenesis, and the methionine cycle. Hudson Science’s 10mg formulation delivers a lower concentration presentation than CSD’s 50mg variant, supplied as a lyophilized powder requiring reconstitution prior to use. A format that preserves compound stability and ensures consistent potency across storage and handling conditions.

The 10mg concentration serves a distinct research purpose within CSD’s 5-Amino-1MQ range. Where the 50mg presentation supports extended protocol timelines and higher dose response evaluations, this 10mg format is particularly well suited to initial dose response characterization studies, titration based protocols examining NNMT inhibition thresholds, and research applications where precise low dose compound availability is a priority variable. The lower unit concentration also provides greater flexibility in comparative study design where multiple concentration points are being evaluated simultaneously across experimental groups.

5-Amino-1MQ’s mechanism of action centers on selective NNMT inhibition, increasing the intracellular SAM to SAH ratio, elevating methyl donor availability across downstream methylation pathways, and producing cascading effects on NAD+ biosynthesis, sirtuin enzyme activation, and mitochondrial biogenesis. NNMT’s high expression in adipose tissue has made this inhibitor class a frequently studied tool compound in obesity, metabolic syndrome, and cellular energy homeostasis research with 5-Amino-1MQ’s selectivity for NNMT over related methyltransferase enzymes making it a valuable reference compound for isolating NNMT specific contributions to metabolic regulation.

Hudson Science formulations are stocked by Canada Steroid Depot following the same rigorous third party lab verification process applied to every product in our range. Each batch is tested for concentration accuracy and purity before being made available, with COA documentation available on request. Researchers comparing options within CSD’s 5-Amino-1MQ range will find both the 10mg and 50mg Hudson Science presentations available, concentration selection representing the primary differentiating variable between the two listings. All orders ship discreetly across Canada in plain, unmarked packaging with no identifying information on the exterior.

Reconstitute with bacteriostatic water prior to use. Store lyophilized powder at 2–8°C away from direct light. Once reconstituted refrigerate and use within 28 days. Intended for research purposes only.

Commonly researched alongside NAD+ precursor compounds in metabolic pathway and energy homeostasis studies. Browse CSD’s full peptide and research compound range for complete sourcing.