HGH 21.5 IU contains human growth hormone (somatropin) supplied as 10 individual vials containing 2.15 IU per vial, providing 21.5 IU total per kit. Somatropin is a recombinant form of human growth hormone designed to reproduce the biological activity of endogenous growth hormone produced naturally by the pituitary gland. Pharmaceutical somatropin is used medically as replacement therapy in adults and children with confirmed growth hormone deficiency, as well as for certain pediatric growth disorders depending on the specific product and indication.
At the cellular level, somatropin binds to growth hormone receptors (GHRs) located on target cell membranes. Activation of these receptors initiates intracellular signaling and increases the production of growth hormone dependent proteins, including insulin like growth factor 1 (IGF-1) and IGF binding proteins. IGF-1 mediates many of growth hormone’s downstream effects on tissue growth and development, while growth hormone also produces several direct metabolic effects.
Growth hormone activity influences several physiological systems. Somatropin can stimulate protein synthesis and cellular growth, influence lipid metabolism and lipolysis, and affect carbohydrate metabolism. In children with growth hormone deficiency, these actions contribute to skeletal growth through effects on the growth plates of long bones. In adults with confirmed growth hormone deficiency, replacement therapy is used to restore deficient GH activity and can influence body composition and metabolic function.
The relationship between HGH and IGF-1 is particularly important when evaluating growth hormone activity. Increased GH-receptor signaling promotes IGF-1 production, particularly in the liver and peripheral tissues, and serum IGF-1 measurements are commonly used clinically when monitoring and adjusting somatropin replacement therapy. Current prescribing information recommends that treatment be individualized according to factors such as clinical response, adverse effects and age and sex adjusted IGF-1 concentrations.
This kit contains:
- Total HGH: 21.5 IU
- Strength Per Vial: 2.15 IU
- Quantity: 10 Vials
- Active Compound: Human Growth Hormone (Somatropin)
Somatropin is a prescription medication in Canada and authorized products are used under medical supervision for specific diagnosed conditions. Health Canada’s Drug Product Database lists somatropin products as prescription medications, including injectable powder and solution formulations.
Growth hormone treatment also has important safety considerations. Somatropin can affect glucose metabolism and insulin sensitivity, and patients with diabetes or risk factors for diabetes may require additional monitoring. Other clinically recognized adverse effects and precautions include fluid retention, joint or muscle discomfort, intracranial hypertension, thyroid function changes and complications in certain susceptible patients. Health Canada advises that somatropin should be used under the supervision of physicians experienced in diagnosing and managing growth hormone disorders.
Somatropin is not indicated as a general treatment for otherwise healthy, non growth hormone deficient adults. Its appropriate use, dose and monitoring requirements should be determined by a qualified healthcare professional based on confirmed clinical need and laboratory assessment.
Storage and reconstitution requirements can vary by formulation and manufacturer. Follow the storage instructions supplied with the specific product and, where the product is supplied in lyophilized form, use the appropriate manufacturer recommended diluent and handling procedure.
