CJC-1295 is a synthetic GHRH analogue incorporating a Drug Affinity Complex (DAC) technology modification. A maleimidoproprionic acid (MPA) side chain that enables covalent binding to circulating albumin following administration, extending the compound’s half-life from the minutes associated with native GHRH to approximately 6–8 days. Hudson Science’s formulation supplies 5mg as a lyophilized vial, preserving peptide structural integrity and potency across storage conditions until reconstitution. The DAC modification’s albumin binding activity requiring an intact peptide structure that lyophilized storage maintains more reliably than aqueous solution across extended research timelines.
CJC-1295’s albumin bound extended half-life produces a fundamentally different pituitary stimulation profile from shorter acting GHRH analogues like Sermorelin. Where Sermorelin’s rapid clearance produces discrete GHRH receptor activation episodes requiring frequent administration, CJC-1295’s sustained albumin bound circulation maintains continuous GHRH receptor availability across a 6–8 day active window, producing what researchers have characterized as a sustained elevation of the GH secretory baseline rather than discrete pulse augmentation alone. This prolonged GHRH receptor engagement profile has made CJC-1295 the most frequently studied long acting GHRH analogue in combination with GHRPs, where its sustained receptor priming complements the acute GH pulse stimulation of Ipamorelin, GHRP-2, and Hexarelin to produce synergistic secretory responses.
CSD stocks three distinct GHRH receptor agonists covering the full half-life spectrum. Sermorelin at the shortest active window with the most adjustable clearance profile, Tesamorelin at an intermediate half-life with FDA approval supporting its clinical literature, and CJC-1295 at the longest active window through DAC mediated albumin binding. CJC-1295 is also available as a pre combined CJC-IPA Blend with Ipamorelin from Hudson Science, giving researchers the option to source the individual compound for custom ratio protocols or the pre combined format for standardized co administration from the same manufacturer and supplier.
Hudson Science formulations are stocked by Canada Steroid Depot following the same rigorous third party lab verification process applied to every product in our range. Each batch is tested for concentration accuracy and purity before being made available, with COA documentation available on request. CSD’s sourcing standards apply uniformly across all manufacturers we carry, and Hudson Science’s CJC-1295 meets those standards consistently. All orders ship discreetly across Canada in plain, unmarked packaging with no identifying information on the exterior.
Reconstitute with bacteriostatic water prior to use. Store lyophilized peptide at 2–8°C away from direct light. Once reconstituted refrigerate and use within 28 days. Intended for research purposes only.
Commonly researched alongside Ipamorelin and GHRP-2 in comparative GH secretagogue combination and GHRH axis stimulation studies. Browse CSD’s full peptide range for complete sourcing.
