Cialis (Tadalafil) 10mg is a PDE5 inhibitor oral tablet formulation supplied in a 50 tablet pack. Manufactured for consistent potency, stability, and research applications.
Format50 Tablets
Concentration10mg
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Tadalafil, widely known by its pharmaceutical brand name Cialis, is a phosphodiesterase type 5 (PDE5) inhibitor with FDA approval for erectile dysfunction and benign prostatic hyperplasia. F40 Biotech’s formulation delivers 10mg per tablet in a 50 count format, consistent with the standard on demand dose referenced in clinical prescribing guidelines.
Tadalafil shares the same fundamental PDE5 inhibition mechanism as Sildenafil, prolonging the cyclic GMP signal triggered by nitric oxide release during sexual stimulation rather than producing an erection independent of stimulation. What meaningfully distinguishes Tadalafil from Sildenafil is its half-life of approximately 17.5 hours, dramatically longer than Sildenafil’s 4 hour half-life. This extended half-life produces a substantially longer window of activity, commonly referenced as up to 36 hours which has made Tadalafil a frequently studied compound for both on demand use and, at lower daily doses, continuous once daily administration for sustained PDE5 inhibition rather than event based dosing.
Tadalafil’s dual FDA approval for benign prostatic hyperplasia (BPH) alongside erectile dysfunction distinguishes its clinical research profile from Sildenafil, which holds approval only for erectile dysfunction and pulmonary arterial hypertension. Tadalafil’s BPH activity is understood to operate through PDE5 inhibition mediated smooth muscle relaxation in the lower urinary tract and prostate, a secondary mechanism that has positioned it as a relevant research compound in comparative studies of PDE5 inhibitor activity across both vascular and smooth muscle tissue beyond the corpus cavernosum.
Every batch of CSD’s Tadalafil is third party lab tested for concentration accuracy and purity before being made available, with COA documentation available on request. CSD stocks both Tadalafil and Sildenafil across multiple formats, giving researchers PDE5 inhibitor compound and half-life comparison flexibility from a single verified Canadian supplier. All orders ship discreetly across Canada in plain, unmarked packaging with no identifying information on the exterior.
Tadalafil should not be combined with nitrate medications, as this combination can cause a dangerous and potentially fatal drop in blood pressure. Consult a healthcare provider before use, particularly if you have cardiovascular conditions or take other medications.
Store in a cool, dry place away from direct light and heat.
Tadalafil (brand name Cialis) is a highly selective PDE5 (phosphodiesterase type 5) inhibitor with the longest half-life of any PDE5 inhibitor, approximately 17.5 hours allowing both on demand dosing and once daily low dose protocols for continuous PDE5 inhibition. Originally developed by Eli Lilly, Tadalafil is FDA approved for erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension (as Adcirca). It is researched for erectile dysfunction, blood pressure reduction through systemic vasodilation, improved exercise blood flow and muscle pump, prostate health maintenance, cardiovascular protection, and pulmonary vascular resistance reduction. Its extended half-life and additional research applications make it the most versatile PDE5 inhibitor in the research catalogue.
The 10mg tablet sits between the 5mg starting dose and the 20mg maximum approved dose — covering the most commonly researched intermediate dose range. For on-demand erectile dysfunction research, 10mg administered 30 minutes before the research window is the standard starting dose with escalation to 20mg if response is insufficient. For daily low dose TRT and anabolic research support protocols targeting blood pressure management and exercise blood flow enhancement, 10mg tablets can be split to deliver 5mg daily, the most commonly researched daily Tadalafil dose. The 50 tablet pack at 10mg provides 500mg total; sufficient for 50 on demand 10mg doses, 100 daily 5mg doses, or 25 maximum 20mg doses using two tablets.
Tadalafil is researched in anabolic contexts for several distinct applications beyond erectile function. Daily low dose Tadalafil (5mg) is studied for blood pressure management; particularly relevant in anabolic protocols where fluid retention or hematocrit elevation elevates blood pressure. Its vasodilatory effects enhance exercise blood flow to working muscle, producing improved muscle pump and potentially enhanced nutrient delivery during training. Tadalafil also demonstrates beneficial effects on benign prostatic hyperplasia, relevant in long term anabolic research where androgenic stimulation of prostate tissue is a management consideration. Its cardioprotective properties through chronic nitric oxide pathway potentiation are also an active area of research.
Tadalafil's 17.5 hour half-life is significantly longer than Sildenafil (4–6 hours) and Vardenafil (4–5 hours) producing a unique pharmacokinetic profile that allows both on demand and daily dosing strategies. For on demand research, a single 10–20mg dose maintains meaningful PDE5 inhibition for up to 36 hours, earning Tadalafil the nickname 'the weekend pill' in clinical research. For daily dosing research, 5mg once daily produces steady state Tadalafil plasma levels within 5 days, providing continuous background PDE5 inhibition that allows spontaneous response without timing requirements. The daily dosing approach is the most commonly studied Tadalafil protocol for cardiovascular and blood pressure research applications.
Yes! This batch has been independently HPLC tested by an accredited third party laboratory confirming concentration accuracy at 10mg per tablet and compound identity as Tadalafil. A certificate of analysis is available.
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