Kisspeptin-10 10mg. Used to support reproductive hormone signaling, fertility, libido, and healthy testosterone production. Lab tested, discreetly shipped across Canada.
FormatLyophilized Vial
ConcentrationDepends on reconstitution with BAC water
Pack Size Selected: 5 Pack
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HPLC verified. COA on file for this batch
Ships from within Canada; No Customs
Discreet plain packaging; always
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Kisspeptin-10 is a 10 amino acid C-terminal fragment of the full length Kisspeptin-54 peptide. The shortest biologically active Kisspeptin fragment that retains full KISS1R (GPR54) receptor binding and downstream signaling activity. iLab Pharma’s formulation supplies 10mg as a lyophilized vial, preserving peptide structural integrity and potency across storage conditions until reconstitution, standard practice for short sequence bioactive peptide fragments where aqueous stability at ambient temperature is limited.
Kisspeptin’s research significance centers on its role as the master upstream regulator of the hypothalamic pituitary gonadal (HPG) axis. A position in reproductive endocrinology research that has generated an extensive and rapidly growing clinical literature since its identification in the early 2000s. Kisspeptin acts through KISS1R receptors on GnRH secreting neurons in the hypothalamus, triggering the pulsatile release of gonadotropin releasing hormone (GnRH) that drives downstream LH and FSH secretion from the pituitary. Ultimately gonadal sex steroid production. This upstream gatekeeper role makes Kisspeptin fundamentally different from every other HPG axis compound in CSD’s range. SERMs like Clomiphene and Tamoxifen modulate HPG axis activity by blocking estrogen feedback at the hypothalamus, HCG mimics LH activity at the gonadal level, and HMG delivers exogenous FSH and LH directly. Kisspeptin operates one step above all of these, at the GnRH neuron level where the HPG axis cascade originates.
Kisspeptin-10’s research applications span reproductive endocrinology, fertility research, and metabolic biology. Its role in puberty initiation has generated investigation into Kisspeptin deficiency and delayed puberty models. Its pulsatile GnRH stimulation mechanism has been studied in research examining male and female reproductive hormone restoration and fertility protocols. Beyond reproduction, KISS1R receptors have been identified in peripheral tissues including the pancreas, liver, and adipose tissue, generating emerging research interest in Kisspeptin’s role in insulin secretion, energy metabolism, and appetite regulation that extends its research profile beyond classical reproductive endocrinology.
iLab Pharma formulations are stocked by Canada Steroid Depot following the same rigorous third party lab verification process applied to every product in our range. Each batch is tested for concentration accuracy and purity before being made available, with COA documentation available on request. CSD’s sourcing standards apply uniformly across all manufacturers we carry, and iLab Pharma’s Kisspeptin-10 meets those standards consistently. All orders ship discreetly across Canada in plain, unmarked packaging with no identifying information on the exterior.
Reconstitute with bacteriostatic water prior to use. Store lyophilized peptide at 2–8°C away from direct light. Once reconstituted refrigerate and use within 28 days. Intended for research purposes only.
Commonly researched alongside GnRH analogues and HPG axis compounds in comparative reproductive endocrinology and gonadotropin regulation studies. Browse CSD’s full peptide range for complete sourcing.
Kisspeptin-10, also known as KP-10 or Metastin 45-54, is a naturally occurring 10 amino acid fragment derived from the KISS1 peptide precursor. It is the shortest endogenous kisspeptin sequence that retains full biological activity at the KISS1 receptor, also known as GPR54. Kisspeptin-10 is primarily studied for its central role in reproductive hormone signalling and regulation of the hypothalamic pituitary gonadal axis. This product contains 10mg of lyophilized Kisspeptin-10 in a single vial for laboratory research.
Kisspeptin-10 is primarily researched in reproductive endocrinology, including regulation of gonadotropin releasing hormone (GnRH), luteinizing hormone (LH), follicle stimulating hormone (FSH), puberty, fertility, ovulatory signaling, and gonadal hormone production. Human studies have demonstrated that Kisspeptin-10 can strongly stimulate LH secretion, making the kisspeptin system an important research target for understanding reproductive hormone regulation.
Kisspeptin-10 activates the KISS1 receptor, or KISS1R/GPR54, within the reproductive neuroendocrine system. This signalling stimulates hypothalamic GnRH release, which in turn acts on the pituitary gland to regulate secretion of LH and FSH. These hormones control downstream reproductive processes including gonadal steroid production, follicular development, ovulation, spermatogenesis, and normal reproductive-axis function.
Kisspeptin-10 and Kisspeptin-54 are both biologically active peptides derived from the same KISS1 precursor and activate the same KISS1 receptor. Kisspeptin-10 consists of the final 10 amino acids shared by the active kisspeptin family, while Kisspeptin-54 contains 54 amino acids. Kisspeptin-10 retains strong receptor activity but is cleared and degraded much more rapidly in vivo, with research reporting a circulating half-life of approximately 4 minutes compared with roughly 30 minutes for Kisspeptin-54.
Yes! This batch is HPLC tested to verify Kisspeptin-10 identity and content accuracy at 10mg per vial. A certificate of analysis is available.
