Diviltac is a combined hormone injection containing algestone acetophenide and estradiol enanthate. Used as a long acting hormonal contraceptive and for management of certain hormone related menstrual conditions. Supplied as a single 1mL ampoule.
Format1mL Ampoule
Concentration150mg Algestone, 10mg Estradiol / mL
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Diviltac is a combined injectable hormonal medication containing 150mg of algestone acetophenide and 10mg of estradiol enanthate per 1mL ampoule. The formulation combines a long acting progestogen with an estrogen and is primarily used as a monthly injectable contraceptive.
Algestone acetophenide, also known as dihydroxyprogesterone acetophenide or DHPA, is a synthetic progesterone derivative that acts as an agonist at progesterone receptors. Estradiol enanthate is a long acting ester of estradiol that produces estrogenic activity through activation of estrogen receptors. Together, the two hormones provide sustained progestogenic and estrogenic effects following intramuscular administration.
The contraceptive action of the combination is primarily associated with suppression of ovulation through hormonal regulation of the hypothalamic pituitary ovarian axis. The progestogenic component also produces changes in cervical mucus and the endometrium that contribute to contraceptive activity, while estradiol provides estrogenic support and assists with cycle control.
Clinical literature has studied the combination of 150mg algestone acetophenide with 10mg estradiol enanthate as a once monthly injectable contraceptive. The formulation has been marketed internationally under several brand names and remains particularly associated with contraceptive use in Latin American markets.
In addition to contraception, algestone/estradiol combinations have been used in some markets for conditions involving menstrual cycle regulation, including dysmenorrhea, abnormal uterine bleeding and endometriosis. The appropriateness of these uses depends on the individual patient and local prescribing information.
Each Diviltac unit contains one 1mL ampoule formulated with:
Algestone Acetophenide: 150mg
Estradiol Enanthate: 10mg
Volume: 1mL
Dosage Form: Injectable solution
Combined estrogen progestogen medications can carry clinically significant risks and contraindications, including an increased risk of blood clots and certain cardiovascular complications in susceptible individuals. Diviltac should therefore be used only under appropriate medical supervision and according to its approved prescribing information.
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Frequently asked questions
Diviltac is a combined hormonal injectable containing 150mg of algestone acetophenide and 10mg of estradiol enanthate in a single 1mL ampoule. Algestone acetophenide provides progestogenic activity, while estradiol enanthate is a long acting estrogen ester. The formulation is supplied as a ready to use intramuscular injectable solution.
Diviltac is primarily used as a monthly combined injectable contraceptive. The algestone acetophenide and estradiol enanthate combination has been studied for suppression of ovulation across the monthly treatment interval. Product information also lists certain menstrual and gynecological applications when prescribed by an appropriate healthcare professional.
Diviltac combines a progestogen with an estrogen to regulate the hypothalamic pituitary ovarian axis and suppress ovulation. The long acting ester and depot characteristics of the two hormones provide sustained hormonal activity following intramuscular administration. Additional contraceptive effects involve changes in cervical mucus and the endometrium.
Algestone acetophenide is a synthetic progestogen that provides progesterone like hormonal activity. Estradiol enanthate is a long acting ester of estradiol that provides estrogenic activity. Diviltac combines both hormone classes in one injection to produce a sustained combined hormonal effect.
No. Diviltac is supplied as a ready to use sterile injectable solution in a 1mL ampoule and does not require reconstitution with bacteriostatic water or another diluent. It is intended for intramuscular administration according to the product prescribing information.
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