MOTS-C – 40mg

MOTS-C (Mitochondrial Open Reading Frame of the Twelve S rRNA type c) is a mitochondria derived peptide encoded within the mitochondrial genome rather than the nuclear genome. A discovery that fundamentally expanded the understood coding capacity of the mitochondrial genome beyond oxidative phosphorylation machinery. iLab Pharma’s formulation supplies 40mg as a lyophilized vial; a higher concentration standalone presentation compared to the 10mg x 2 MOTS-C component included in CSD’s iLab Pharma Anti Aging Peptide Stack, suited to extended research protocols or higher dose response evaluations requiring significant compound availability from a single vial supply.

MOTS-C’s primary research mechanism centers on AMPK (AMP activated protein kinase) pathway activation through mitochondria to nucleus translocation in response to metabolic stress. By translocating from the mitochondria to the nucleus, MOTS-C directly influences nuclear gene expression. A mitochondria to nucleus retrograde signaling pathway that represents a novel mechanism of metabolic regulation not previously attributed to mitochondrially encoded peptides. AMPK activation downstream of MOTS-C signaling promotes glucose uptake, fatty acid oxidation, and mitochondrial biogenesis while suppressing energy consuming anabolic pathways. Coordinated metabolic response that has generated significant research interest in insulin sensitivity, exercise mimetics, obesity, and age related metabolic decline studies.

CSD stocks MOTS-C across two standalone formats, this iLab Pharma 40mg lyophilized vial and the F40 Biotech 60mg prefilled pen presentation; alongside its inclusion as a component in the iLab Pharma Anti Aging Peptide Stack at 10mg per vial. Researchers selecting between formats will find the base compound and pharmacological characteristics consistent across all presentations, with concentration, manufacturer, and delivery format representing the primary selection variables. The 40mg lyophilized vial is particularly well suited to researchers requiring precise reconstitution control and flexible dosing across extended protocols, while the 60mg prefilled pen offers ready to use convenience for consistent repeated administration.

iLab Pharma formulations are stocked by Canada Steroid Depot following the same rigorous third party lab verification process applied to every product in our range. Each batch is tested for concentration accuracy and purity before being made available, with COA documentation available on request. CSD’s sourcing standards apply uniformly across all manufacturers we carry, and iLab Pharma’s MOTS-C meets those standards consistently. All orders ship discreetly across Canada in plain, unmarked packaging with no identifying information on the exterior.

Reconstitute with bacteriostatic water prior to use. Store lyophilized peptide at 2–8°C away from direct light. Once reconstituted refrigerate and use within 28 days. Intended for research purposes only.

Commonly researched alongside Epithalon and NAD+ in comparative longevity and mitochondrial metabolic regulation studies. Browse CSD’s full peptide range for complete sourcing.