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MOTS-C 40mg. Used to support energy, metabolism, exercise performance, and healthy body composition. Lab tested, discreetly shipped across Canada.
FormatLyophilized Vial
ConcentrationDependent on reconstitution with BAC water
Pack Size Selected: 5 Pack
Pay with Interac e-Transfer or Crypto
HPLC verified. COA on file for this batch
Ships from within Canada; No Customs
Discreet plain packaging; always
24h dispatch; Tracked Delivery
MOTS-C (Mitochondrial Open Reading Frame of the Twelve S rRNA type c) is a mitochondria derived peptide encoded within the mitochondrial genome rather than the nuclear genome. A discovery that fundamentally expanded the understood coding capacity of the mitochondrial genome beyond oxidative phosphorylation machinery. iLab Pharma’s formulation supplies 40mg as a lyophilized vial; a higher concentration standalone presentation compared to the 10mg x 2 MOTS-C component included in CSD’s iLab Pharma Anti Aging Peptide Stack, suited to extended research protocols or higher dose response evaluations requiring significant compound availability from a single vial supply.
MOTS-C’s primary research mechanism centers on AMPK (AMP activated protein kinase) pathway activation through mitochondria to nucleus translocation in response to metabolic stress. By translocating from the mitochondria to the nucleus, MOTS-C directly influences nuclear gene expression. A mitochondria to nucleus retrograde signaling pathway that represents a novel mechanism of metabolic regulation not previously attributed to mitochondrially encoded peptides. AMPK activation downstream of MOTS-C signaling promotes glucose uptake, fatty acid oxidation, and mitochondrial biogenesis while suppressing energy consuming anabolic pathways. Coordinated metabolic response that has generated significant research interest in insulin sensitivity, exercise mimetics, obesity, and age related metabolic decline studies.
CSD stocks MOTS-C across two standalone formats, this iLab Pharma 40mg lyophilized vial and the F40 Biotech 60mg prefilled pen presentation; alongside its inclusion as a component in the iLab Pharma Anti Aging Peptide Stack at 10mg per vial. Researchers selecting between formats will find the base compound and pharmacological characteristics consistent across all presentations, with concentration, manufacturer, and delivery format representing the primary selection variables. The 40mg lyophilized vial is particularly well suited to researchers requiring precise reconstitution control and flexible dosing across extended protocols, while the 60mg prefilled pen offers ready to use convenience for consistent repeated administration.
iLab Pharma formulations are stocked by Canada Steroid Depot following the same rigorous third party lab verification process applied to every product in our range. Each batch is tested for concentration accuracy and purity before being made available, with COA documentation available on request. CSD’s sourcing standards apply uniformly across all manufacturers we carry, and iLab Pharma’s MOTS-C meets those standards consistently. All orders ship discreetly across Canada in plain, unmarked packaging with no identifying information on the exterior.
Reconstitute with bacteriostatic water prior to use. Store lyophilized peptide at 2–8°C away from direct light. Once reconstituted refrigerate and use within 28 days. Intended for research purposes only.
Commonly researched alongside Epithalon and NAD+ in comparative longevity and mitochondrial metabolic regulation studies. Browse CSD’s full peptide range for complete sourcing.
MOTS-c, short for Mitochondrial ORF of the 12S rRNA Type-c, is a naturally occurring mitochondrial derived peptide composed of 16 amino acids. Unlike most peptides encoded by nuclear DNA, MOTS-c originates from a small open reading frame within mitochondrial DNA. It is studied as a signaling molecule involved in communication between mitochondria and the rest of the cell, particularly in pathways regulating metabolism, cellular stress responses, and energy homeostasis. This product contains 40mg of lyophilized MOTS-c in a single vial for laboratory research.
MOTS-c is primarily investigated in metabolic and mitochondrial research. Experimental studies have examined its effects on glucose utilization, insulin sensitivity, skeletal muscle metabolism, cellular energy regulation, mitochondrial function, metabolic stress responses, exercise adaptation, and age related metabolic changes. Preclinical research has also explored its potential role in obesity, metabolic dysfunction, and cellular resilience, although these findings do not establish therapeutic benefits in humans.
Research indicates that MOTS-c can alter cellular metabolism through pathways involving AMP activated protein kinase (AMPK), an important cellular energy sensor. Experimental studies suggest MOTS-c can promote glucose utilization and influence folate and purine metabolism, helping cells adapt to changes in energy demand. Under metabolic stress, MOTS-c has also been reported to participate in mitochondrial to nuclear signaling that alters expression of genes involved in cellular adaptation and homeostasis.
MOTS-c is closely studied in skeletal muscle because mitochondrial energy production and glucose metabolism are essential to muscle function during physical activity. Experimental research has reported that MOTS-c influences skeletal muscle glucose utilization, metabolic flexibility, mitochondrial signaling, and adaptive responses associated with exercise. Research has also observed relationships between MOTS-c, aging, and physical capacity, making it a compound of interest in studies of metabolic health and age related changes in muscle function.
Yes! This batch is HPLC tested to verify MOTS-c identity and content accuracy at 40mg per vial. A certificate of analysis is available.
