ARA-290 – 10mg

ARA-290 is a synthetic 11-amino acid peptide derived from the helix B surface of erythropoietin (EPO) specifically engineered to selectively activate the innate repair receptor (IRR) while eliminating the erythropoietic and thrombotic activity associated with full length EPO administration. Hudson Science’s formulation supplies 10mg as a lyophilized vial, preserving peptide structural integrity and potency across storage conditions until reconstitution. Standard practice for synthetic peptides of this class where aqueous stability at ambient temperature is limited.

The structural engineering behind ARA-290 is its defining research characteristic. Full length erythropoietin activates two distinct receptor systems;  the classical EPO receptor homodimer driving red blood cell production and platelet activity, and the tissue protective innate repair receptor heterodimer mediating cytoprotective and anti inflammatory responses in non hematopoietic tissue. ARA-290’s design isolates the helix B sequence responsible for IRR binding while eliminating the receptor binding domains associated with erythropoietic activity producing a compound with selective tissue protective and anti inflammatory signaling activity uncoupled from the hematopoietic and cardiovascular risks associated with EPO administration. This receptor selectivity makes ARA-290 a uniquely valuable research tool for studying EPO’s cytoprotective mechanisms in isolation from its erythropoietic activity.

ARA-290’s research literature spans several clinically relevant areas where IRR mediated tissue protection has been investigated. Neuropathic pain modulation has been a primary research focus. ARA-290 has been studied in clinical trials examining painful diabetic neuropathy, with documented effects on small nerve fiber regeneration and inflammatory cytokine reduction in affected tissue. Additional documented research areas include pancreatic beta cell protection, wound healing, and systemic inflammation modulation; a diverse tissue protective research profile that reflects the broad distribution of IRR receptors across multiple organ systems and the growing research interest in EPO derived tissue protection peptides as a distinct compound class from erythropoietic agents.

Hudson Science formulations are stocked by Canada Steroid Depot following the same rigorous third party lab verification process applied to every product in our range. Each batch is tested for concentration accuracy and purity before being made available, with COA documentation available on request. CSD’s sourcing standards apply uniformly across all manufacturers we carry, and Hudson Science’s ARA-290 meets those standards consistently. All orders ship discreetly across Canada in plain, unmarked packaging with no identifying information on the exterior.

Reconstitute with bacteriostatic water prior to use. Store lyophilized peptide at 2–8°C away from direct light. Once reconstituted refrigerate and use within 28 days. Intended for research purposes only.

Commonly researched alongside BPC-157 and TB-500 in comparative tissue protection and anti inflammatory peptide studies. Browse CSD’s full peptide range for complete sourcing.