PT-141 10mg Nasal Spray – 100mcg/Spray

PT-141, known chemically as Bremelanotide, is a synthetic melanocortin peptide and direct metabolite of Melanotan II — produced through the removal of the C terminal amide group from the MT-2 structure. Hudson Science’s formulation delivers 10mg total PT-141 at 100mcg per metered spray in a nasal delivery system, the same delivery format and concentration as CSD’s Melanotan II nasal spray listing, with the two compounds representing closely related but pharmacologically distinct research subjects within the melanocortin receptor family.

The structural relationship between PT-141 and Melanotan II is an important research distinction. Where Melanotan II acts broadly across MC1R, MC3R, and MC4R receptor subtypes; producing pigmentation, appetite, and metabolic effects alongside its central melanocortin activity. PT-141’s research profile is more specifically focused on MC3R and MC4R central nervous system activity, with significantly reduced MC1R melanogenic activity compared to its parent compound. This receptor selectivity shift makes PT-141 a more targeted research tool for studies examining hypothalamic melanocortin signaling pathways independent of pigmentation endpoints. PT-141 achieved FDA approval under the brand name Vyleesi for hypoactive sexual desire disorder; one of the few melanocortin peptides to reach regulatory approval contributing a well documented human clinical literature base that distinguishes it from most research peptide compounds in this class.

The nasal spray format is particularly relevant for PT-141’s primary research targets. MC3R and MC4R receptors are concentrated in hypothalamic regions of the brain; centrally located targets where nasal delivery’s proximity to the olfactory epithelium and potential olfactory nerve CNS access pathway provides a meaningful pharmacokinetic advantage over peripheral administration routes. CSD stocks both PT-141 and Melanotan II in matched 10mg nasal spray presentations at 100mcg per spray, allowing researchers to conduct direct comparative melanocortin receptor selectivity studies between the two closely related compounds from a single verified Canadian supplier.

Hudson Science formulations are stocked by Canada Steroid Depot following the same rigorous third party lab verification process applied to every product in our range. Each batch is tested for concentration accuracy and purity before being made available, with COA documentation available on request. CSD’s sourcing standards apply uniformly across all manufacturers we carry, and Hudson Science’s PT-141 nasal spray meets those standards consistently. All orders ship discreetly across Canada in plain, unmarked packaging with no identifying information on the exterior.

Store at 2–8°C away from direct light. Do not freeze. Keep upright. Intended for research purposes only.

Commonly researched alongside Melanotan II in comparative melanocortin receptor selectivity and central nervous system signalling studies. Browse CSD’s full peptide range for complete sourcing.