SS31 – 10mg

SS-31 (Szeto Schiller peptide 31), also known as Elamipretide, is a synthetic tetrapeptide belonging to the Szeto Schiller family of mitochondria targeted peptides, compounds specifically engineered to concentrate within the inner mitochondrial membrane through electrostatic and hydrophobic interactions with cardiolipin, a phospholipid unique to the inner mitochondrial membrane that is essential for mitochondrial cristae architecture and electron transport chain function. iLab Pharma’s formulation supplies 10mg as a lyophilized vial, preserving peptide structural integrity and potency across storage conditions until reconstitution.

SS-31’s mechanism of action is defined by its selective cardiolipin binding, a targeting specificity that concentrates the peptide approximately 1000 fold within the inner mitochondrial membrane relative to cytoplasmic concentrations. Cardiolipin interaction stabilizes mitochondrial cristae architecture, supports cytochrome c association with the inner membrane, and reduces electron leak from the electron transport chain. The primary source of mitochondrial reactive oxygen species (ROS) production. By reducing electron leak rather than scavenging ROS after production, SS-31 addresses mitochondrial oxidative stress at its source rather than downstream, a mechanistic distinction from conventional antioxidant compounds that has generated significant research interest in studies examining mitochondrial dysfunction across ageing, ischaemia reperfusion injury, heart failure, and neurodegenerative disease models.

SS-31’s research profile spans several high priority areas in contemporary mitochondrial biology. Its cardiolipin stabilising activity has been studied in cardiac research examining heart failure and ischaemia reperfusion injury contexts where mitochondrial cristae disruption and cytochrome c release are well established pathological mechanisms. Renal research examining acute kidney injury and chronic kidney disease has documented SS-31’s protective effects on tubular cell mitochondrial function. Neurodegenerative research has examined its activity in models of Alzheimer’s disease and Parkinson’s disease where mitochondrial dysfunction is a central pathological feature. This breadth of documented research activity across multiple organ systems reflects SS-31’s fundamental mechanism targeting a universal mitochondrial structure rather than a tissue specific pathway. Making it one of the most broadly applicable mitochondrial research compounds currently available.

iLab Pharma formulations are stocked by Canada Steroid Depot following the same rigorous third party lab verification process applied to every product in our range. Each batch is tested for concentration accuracy and purity before being made available, with COA documentation available on request. CSD’s sourcing standards apply uniformly across all manufacturers we carry, and iLab Pharma’s SS-31 meets those standards consistently. All orders ship discreetly across Canada in plain, unmarked packaging with no identifying information on the exterior.

Reconstitute with bacteriostatic water prior to use. Store lyophilized peptide at 2–8°C away from direct light. Once reconstituted refrigerate and use within 28 days. Intended for research purposes only.

Commonly researched alongside MOTS-C and NAD+ in comparative mitochondrial function and cellular energy regulation studies. Browse CSD’s full peptide and research compound range for complete sourcing.