YK-11 occupies an unusual position within the SARM research category, it is structurally a steroidal compound derived from DHT, technically classifying it as a synthetic steroid rather than a true non steroidal SARM like LGD-4033 or S23, yet it produces a SARM like partial androgen receptor agonist activity profile that has led to its common grouping alongside the SARM compound class in research literature. F40 Biotech’s formulation delivers 10mg per tablet in a 50 count format, consistent with the concentration most commonly referenced in preclinical YK-11 research.
YK-11’s most distinctive and research relevant characteristic is its documented activity as a myostatin inhibitor, a mechanism entirely separate from its androgen receptor binding activity and unique among CSD’s SARM range. Myostatin is a TGF-β superfamily member that functions as the primary negative regulator of skeletal muscle growth, similarly to the mechanism through which Follistatin 344 antagonizes myostatin signaling. YK-11 has been documented in preclinical research to increase follistatin expression while directly suppressing myostatin gene expression in muscle satellite cells, producing a dual mechanism where androgen receptor partial agonism and myostatin pathway suppression operate simultaneously through structurally and functionally independent pathways within the same compound.
This dual mechanism distinguishes YK-11’s research profile fundamentally from every other compound in CSD’s SARM range. LGD-4033 and S23 operate purely through androgen receptor binding selectivity without myostatin pathway involvement. YK-11’s myostatin suppression activity creates a direct mechanistic parallel to Follistatin 344’s research applications — both compounds are studied for their influence on the myostatin mediated brake on muscle growth, though through entirely different molecular approaches: Follistatin 344 sequesters myostatin directly as a binding protein, while YK-11 appears to suppress myostatin gene expression at the transcriptional level while simultaneously activating androgen receptor signaling through its steroidal DHT derived structure.
F40 Biotech formulations are stocked by Canada Steroid Depot following the same rigorous third party lab verification process applied to every product in our range. Each batch is tested for concentration accuracy and purity before being made available, with COA documentation available on request. CSD’s sourcing standards apply uniformly across all manufacturers we carry, and F40 Biotech’s YK-11 meets those standards consistently. All orders ship discreetly across Canada in plain, unmarked packaging with no identifying information on the exterior.
Store in a cool, dry place away from direct light and heat. Intended for research purposes only.
Commonly researched alongside Follistatin 344 in comparative myostatin pathway and muscle growth regulation studies. Browse CSD’s full SARM and peptide range for complete sourcing.









JS (verified owner) –
Ultra-fast delivery alongside exceptional customer care!
The tablets split very easily in two to divide the dose (AM and PM) without crumbling.
Anonymous (verified owner) –